MGMT Methylation and Differential Survival Impact by Sex in Glioblastoma

<b>Introduction</b>: Sex differences in glioblastoma (GBM) have been observed in incidence, genetic and epigenetic alterations, and immune response. These differences have extended to the methylation of the MGMT promoter, which critically impacts temozolomide resistance. However, the ass...

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Bibliographic Details
Main Authors: Addison E. Barnett, Ahmad Ozair, Anas S. Bamashmos, Hong Li, David S. Bosler, Gabrielle Yeaney, Assad Ali, David M. Peereboom, Justin D. Lathia, Manmeet S. Ahluwalia
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/7/1374