Differential gene expression analysis by RNA-seq reveals the importance of actin cytoskeletal proteins in erythroleukemia cells

Differential gene expression analysis by RNA-seq reveals the importance of actin cytoskeletal proteins in erythroleukemia cells

Development of drug resistance limits the effectiveness of anticancer treatments. Understanding the molecular mechanisms triggering this event in tumor cells may lead to improved therapeutic strategies. Here we used RNA-seq to compare the transcriptomes of a murine erythroleukemia cell line (MEL) an...

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Bibliographic Details
Main Authors: Vanessa Fernández-Calleja, Pablo Hernández, Jorge B. Schvartzman, Mario García de Lacoba, Dora B. Krimer
Format: Article
Language:English
Published: PeerJ Inc. 2017-06-01
Series:PeerJ
Subjects:
RNA-seq
Cell differentiation
HMBA-resistant
Wiskott-Aldrich syndrome
Bruton’s tyrosine kinase
Erytrhroleukemia cells
Online Access:https://peerj.com/articles/3432.pdf

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https://peerj.com/articles/3432.pdf

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