FluoMALDI Microscopy: Matrix Co‐Crystallization Simultaneously Enhances Fluorescence and MALDI Imaging

FluoMALDI Microscopy: Matrix Co‐Crystallization Simultaneously Enhances Fluorescence and MALDI Imaging

Abstract Here, the authors report that co‐crystallization of fluorophores with matrix‐assisted laser desorption/ionization (MALDI) imaging matrices significantly enhances fluorophore brightness up to 79‐fold, enabling the amplification of innate tissue autofluorescence. This discovery facilitates Fl...

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Bibliographic Details
Main Authors: Ethan Yang, Xinyi Elaine Shen, Hoku West‐Foyle, Tae‐Hun Hahm, Maxime A. Siegler, Dalton R. Brown, Cole C. Johnson, Jeong Hee Kim, LaToya Ann Roker, Caitlin M. Tressler, Ishan Barman, Scot C. Kuo, Kristine Glunde
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Advanced Science
Subjects:
co‐crystallization
FluoMALDI
fluorescence
imaging
MALDI imaging
mass spectrometry
Online Access:https://doi.org/10.1002/advs.202304343

Internet

https://doi.org/10.1002/advs.202304343

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