Deregulated Gene Expression Profiles and Regulatory Networks in Adult and Pediatric RUNX1/RUNX1T1-Positive AML Patients

Acute myeloid leukemia (AML) is a heterogeneous and complex disease concerning molecular aberrations and prognosis. RUNX1/RUNX1T1 is a fusion oncogene that results from the chromosomal translocation t(8;21) and plays a crucial role in AML. However, its impact on the transcriptomic profile of differe...

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Bibliographic Details
Main Authors: Peggy Kanellou, Ilias Georgakopoulos-Soares, Apostolos Zaravinos
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/6/1795