α1-adrenergic stimulation increases ventricular action potential duration in the intact mouse heart

The role of α1-adrenergic receptors (α-ARs) in the regulation of myocardial function is less well-understood than that of β-ARs. Previous reports in the mouse heart have described that α1-adrenergic stimulation shortens action potential duration in isolated cells or tissues, in contrast to prolongat...

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Bibliographic Details
Main Authors: William Joyce, Koen T. Scholman, Bjarke Jensen, Tobias Wang, Bastiaan J. Boukens
Format: Article
Language:English
Published: Canadian Science Publishing 2021-01-01
Series:FACETS
Subjects:
Online Access:https://doi.org/10.1139/facets-2020-0081