Could Immune Checkpoint Disorders and EBV Reactivation Be Connected in the Development of Hematological Malignancies in Immunodeficient Patients?

Could Immune Checkpoint Disorders and EBV Reactivation Be Connected in the Development of Hematological Malignancies in Immunodeficient Patients?

Primary immunodeficiencies (PIDs) and secondary immunodeficiencies (SIDs) are characterized by compromised immune function, rendering individuals susceptible to infections and potentially influencing cancer development. Epstein–Barr virus (EBV), a widespread herpesvirus, has been linked to cancer, p...

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Bibliographic Details
Main Authors: Paulina Mertowska, Sebastian Mertowski, Konrad Smolak, Gabriela Kita, Katarzyna Guz, Aleksandra Kita, Marcin Pasiarski, Jolanta Smok-Kalwat, Stanisław Góźdź, Ewelina Grywalska
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
immunodeficiency
Epstein–Barr virus (EBV)
PD-1
PD-L1
CTLA-4
CD86
Online Access:https://www.mdpi.com/2072-6694/15/19/4786

Internet

https://www.mdpi.com/2072-6694/15/19/4786

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