TRIM22 induces cellular senescence by targeting PHLPP2 in hepatocellular carcinoma
Abstract The ubiquitin-proteasome system is a vital protein degradation system that is involved in various cellular processes, such as cell cycle progression, apoptosis, and differentiation. Dysregulation of this system has been implicated in numerous diseases, including cancer, vascular disease, an...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-01-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-024-06427-w |