Towards development of aptamers that specifically bind to lactate dehydrogenase of Plasmodium falciparum through epitopic targeting

Towards development of aptamers that specifically bind to lactate dehydrogenase of Plasmodium falciparum through epitopic targeting

Abstract Background Early detection is crucial for the effective treatment of malaria, particularly in those cases infected with Plasmodium falciparum. There is a need for diagnostic devices with the capacity to distinguish P. falciparum from other strains of malaria. Here, aptamers generated agains...

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Bibliographic Details
Main Authors: Kelly-Anne Frith, Ronen Fogel, J. P. Dean Goldring, Robert G. E. Krause, Makobetsa Khati, Heinrich Hoppe, Mary E. Cromhout, Meesbah Jiwaji, Janice L. Limson
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Malaria Journal
Subjects:
Aptamer
Oligonucleotide
Lactate dehydrogenase
Malaria
Biorecognition
Detection
Online Access:http://link.springer.com/article/10.1186/s12936-018-2336-z

Internet

http://link.springer.com/article/10.1186/s12936-018-2336-z

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