Methylation mediated Gadd45β enhanced the chemosensitivity of hepatocellular carcinoma by inhibiting the stemness of liver cancer cells

Methylation mediated Gadd45β enhanced the chemosensitivity of hepatocellular carcinoma by inhibiting the stemness of liver cancer cells

Abstract Background Defects of the growth arrest DNA damage-inducible gene 45β (Gadd45β) play an important role in the progression of tumor and confer resistance to chemotherapy. However, the role of Gadd45β in the apoptosis of hepatocellular carcinoma is still not clear. Purpose of this study was t...

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Bibliographic Details
Main Authors: Xiao-Juan Hou, Qiu-Dong Zhao, Ying-Ying Jing, Zhi-Peng Han, Xue Yang, Li-Xin Wei, Yu-Ting Zheng, Feng Xie, Bai-He Zhang
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Cell & Bioscience
Subjects:
Hepatocellular carcinoma
Gadd45β methylation
Apoptosis
Stemness
Online Access:http://link.springer.com/article/10.1186/s13578-017-0189-8

Internet

http://link.springer.com/article/10.1186/s13578-017-0189-8

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