A metazoan/plant-like capping enzyme and cap modified nucleotides in the unicellular eukaryote Trichomonas vaginalis.

The cap structure of eukaryotic messenger RNAs is initially elaborated through three enzymatic reactions: hydrolysis of the 5'-triphosphate, transfer of guanosine through a 5'-5' triphosphate linkage and N7-methylation of the guanine cap. Three distinctive enzymes catalyze each reacti...

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Bibliographic Details
Main Authors: Augusto Simoes-Barbosa, Robert P Hirt, Patricia J Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2904801?pdf=render