DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-Induced Hepatic SteatosisSummary

DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-Induced Hepatic SteatosisSummary

Background & Aims: Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity and mortality whereas the pathogenic mechanism remains largely elusive. DNA N6-methyladenosine (6mA) modification is a recently identified epigenetic mark indicative of transcription in eu...

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Bibliographic Details
Main Authors: Liping Luo, Ya Liu, Paul Nizigiyimana, Mingsheng Ye, Ye Xiao, Qi Guo, Tian Su, Xianghang Luo, Yan Huang, Haiyan Zhou
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
DNA 6mA
ALKBH1
Demethylation
Fatty Liver
Lipid Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22001928

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X22001928

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