Calcium sensing receptor regulate claudin-14 via PKA-STAT3 pathway in rat model of nephrolithiasis

Calcium sensing receptor regulate claudin-14 via PKA-STAT3 pathway in rat model of nephrolithiasis

BackgroundThe calcium-sensitive receptor (CaSR) has been identified as a key factor in the formation of kidney stones. A substantial body of research has illuminated the function of CaSR in stone formation with respect to oxidative stress, epithelial injury, crystal adhesion, and stone-associated pr...

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Bibliographic Details
Main Authors: Peiyue Luo, Tao Chen, Liying Zheng, Junrong Zou, Jun Zou, Wei Li, Qi Chen, Le Cheng, Biao Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
kidney stones
calcium-sensitive receptor
claudin-14
calcium oxalate
signal transducer and activator of transcription 3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1477122/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1477122/full

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