An Efficient Modern Strategy to Screen Drug Candidates Targeting RdRp of SARS-CoV-2 With Potentially High Selectivity and Specificity

An Efficient Modern Strategy to Screen Drug Candidates Targeting RdRp of SARS-CoV-2 With Potentially High Selectivity and Specificity

Desired drug candidates should have both a high potential binding chance and high specificity. Recently, many drug screening strategies have been developed to screen compounds with high possible binding chances or high binding affinity. However, there is still no good solution to detect whether thos...

Full description

Bibliographic Details
Main Authors: Haiping Zhang, Xiaohua Gong, Yun Peng, Konda Mani Saravanan, Hengwei Bian, John Z. H. Zhang, Yanjie Wei, Yi Pan, Yang Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Chemistry
Subjects:
antiviral agent
RdRp
compound specificity estimation
virtual screening
tubeimoside III
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.933102/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.933102/full

Similar Items