csi-miR-96-5p delivered by Clonorchis sinensis extracellular vesicles promotes intrahepatic cholangiocarcinoma proliferation and migration via the ferroptosis-related PTEN/SLC7A11/GPX4 axis

csi-miR-96-5p delivered by Clonorchis sinensis extracellular vesicles promotes intrahepatic cholangiocarcinoma proliferation and migration via the ferroptosis-related PTEN/SLC7A11/GPX4 axis

Abstract Background Clonorchis sinensis (CS) is classified as a group 1 carcinogen and can cause intrahepatic cholangiocarcinoma (ICC). CS extracellular vesicles (CsEVs) play important roles in mediating communication between parasitic helminths and humans. Ferroptosis is a novel cell death mechanis...

Full description

Bibliographic Details
Main Authors: Li-Jia Wen, Ji-Gang Yin, Yong-Xin Wang, Kai Liu, Ji-Xue Zhao
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Parasites & Vectors
Subjects:
Clonorchis sinensis
Extracellular vesicle
miRNA
Cholangiocarcinoma
Ferroptosis
Online Access:https://doi.org/10.1186/s13071-023-06075-7

Internet

https://doi.org/10.1186/s13071-023-06075-7

Similar Items