CX3CL1-induced CD16+ monocytes extravasation in myeloperoxidase-ANCA-associated vasculitis correlates with renal damage

CX3CL1-induced CD16+ monocytes extravasation in myeloperoxidase-ANCA-associated vasculitis correlates with renal damage

BackgroundMonocytes are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Monocyte/macrophages are the dominant infiltrating cells in the glomeruli of patients with myeloperoxidase-AAV (MPO-AAV). However, how human monocyte subsets extravasate to the kidney in MPO-AAV with renal dama...

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Bibliographic Details
Main Authors: Jiale Tang, Zhonghua Liao, Liying Luo, Shuanglinzi Deng, Yuanyuan Jiang, Fangyuan Wang, Xinyue Hu, Hongling Yin, Guanghui Gong, Juntao Feng, Xiaozhao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis
CD16+ monocyte
glomerular endothelial cells
CX3CL1
renal damage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.929244/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.929244/full

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