Reverse development of vaccines against antimicrobial-resistant pathogens

Abstract Vaccine R&D is typically a lengthy process taking >10 years. However, vaccines still fail in clinical development because of unreliable animal models or absent immunological correlates of protection. Without a correlate of protection, phase-1 and -2 studies of safety and immunogenici...

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Bibliographic Details
Main Authors: Fabio Bagnoli, Ilaria Galgani, V. Kumaran Vadivelu, Sanjay Phogat
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00858-4