Reverse development of vaccines against antimicrobial-resistant pathogens
Abstract Vaccine R&D is typically a lengthy process taking >10 years. However, vaccines still fail in clinical development because of unreliable animal models or absent immunological correlates of protection. Without a correlate of protection, phase-1 and -2 studies of safety and immunogenici...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-024-00858-4 |