Rapid Detection of Measles Virus Using Reverse Transcriptase/Recombinase Polymerase Amplification Coupled with CRISPR/Cas12a and a Lateral Flow Detection: A Proof-of-Concept Study

Rapid Detection of Measles Virus Using Reverse Transcriptase/Recombinase Polymerase Amplification Coupled with CRISPR/Cas12a and a Lateral Flow Detection: A Proof-of-Concept Study

The measles virus is highly contagious, and efforts to simplify its diagnosis are essential. A reverse transcriptase/recombinase polymerase amplification assay coupled with CRISPR/Cas12a and an immunochromatographic lateral flow detection (RT-RPA-CRISPR-LFD) was developed for the simple visual detec...

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Bibliographic Details
Main Authors: Elena Pinchon, Steven Henry, Fanny Leon, Chantal Fournier-Wirth, Vincent Foulongne, Jean-François Cantaloube
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Diagnostics
Subjects:
measles virus
reverse transcription
recombinase polymerase amplification
CRISPR/Cas12
Online Access:https://www.mdpi.com/2075-4418/14/5/517

Internet

https://www.mdpi.com/2075-4418/14/5/517

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