Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions

Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions

Paeoniflorin (PF) is a monoterpene glucoside with various biological properties, and it suppresses allergic and inflammatory responses in a rat model of urticaria-like lesions (UL). In the present study, we treated OVA-induced mice presenting UL with PF at four circadian time points (ZT22, ZT04, ZT1...

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Bibliographic Details
Main Authors: Li Peng, Lijuan Wen, Jie Zhang, Xiaotong Zhang, Qin Wei, Jing Guo, Jinhao Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Pharmacology
Subjects:
urticaria-like lesion
paeoniflorin
allergic response
inflammatory cell infiltration
inflammatory cytokine
chronotherapeutic
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.639580/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.639580/full

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