Skeletal muscle overexpression of sAnk1.5 in transgenic mice does not predispose to type 2 diabetes

Skeletal muscle overexpression of sAnk1.5 in transgenic mice does not predispose to type 2 diabetes

Abstract Genome-wide association studies (GWAS) and cis-expression quantitative trait locus (cis-eQTL) analyses indicated an association of the rs508419 single nucleotide polymorphism (SNP) with type 2 diabetes (T2D). rs508419 is localized in the muscle-specific internal promoter (P2) of the ANK1 ge...

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Main Authors: E. Pierantozzi, L. Raucci, S. Buonocore, E. M. Rubino, Q. Ding, A. Laurino, F. Fiore, M. Soldaini, J. Chen, D. Rossi, P. Vangheluwe, H. Chen, V. Sorrentino
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35393-0

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https://doi.org/10.1038/s41598-023-35393-0

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