Fibronectin Deposition Participates in Extracellular Matrix Assembly and Vascular Morphogenesis.

The extracellular matrix (ECM) has been demonstrated to facilitate angiogenesis. In particular, fibronectin has been documented to activate endothelial cells, resulting in their transition from a quiescent state to an active state in which the cells exhibit enhanced migration and proliferation. The...

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Bibliographic Details
Main Authors: Abigail Hielscher, Kim Ellis, Connie Qiu, Josh Porterfield, Sharon Gerecht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4728102?pdf=render