Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivo.
Understanding the role of cytotoxic T lymphocytes (CTLs) in controlling HIV-1 infection is vital for vaccine design. However, it is difficult to assess the importance of CTLs in natural infection. Different human leukocyte antigen (HLA) class I alleles are associated with different rates of progress...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-04-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC1395353?pdf=render |