Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determination
Seaweeds possess considerable potential for developing and enhancing pharmaceutical drugs because of their wide variety as abundant sources of numerous bioactive secondary metabolites, making them well-suited for developing and enhancing pharmaceutical drugs. This study evaluated the antioxidant, se...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Food Chemistry Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772753X23003866 |
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| author | Mohammad Khairul Alam Sobuj Morshed Shamim Shemul Md. Shoebul Islam Md. Ariful Islam Shayla Sultana Mely Mehedi Hasan Ayon Shahittya Mitra Pranto Mohammad Shafiqul Alam Mohammad Sarfuddin Bhuiyan S.M. Rafiquzzaman |
| author_facet | Mohammad Khairul Alam Sobuj Morshed Shamim Shemul Md. Shoebul Islam Md. Ariful Islam Shayla Sultana Mely Mehedi Hasan Ayon Shahittya Mitra Pranto Mohammad Shafiqul Alam Mohammad Sarfuddin Bhuiyan S.M. Rafiquzzaman |
| author_sort | Mohammad Khairul Alam Sobuj |
| collection | DOAJ |
| description | Seaweeds possess considerable potential for developing and enhancing pharmaceutical drugs because of their wide variety as abundant sources of numerous bioactive secondary metabolites, making them well-suited for developing and enhancing pharmaceutical drugs. This study evaluated the antioxidant, secondary metabolites, total phenolic content, and total flavonoid content of various crude extracts (methanol, ethanol) and their fractions (50 % and 70 %) of Sargassum polycystum. Fourier transform infrared (FT‐IR) analysis was also performed to identify the active chemical composition of the crude extracts. The results showed that various extracts contained varying concentrations of terpenoid, saponin, phlobatannin, cardiac glycosides, phenolic, and flavonoid. FT-IR analysis confirmed the presence of phenols, carboxylic acid, ketones, ethers, aromatics, amides, and sulfonates. 100 % methanolic extract contained the maximum concentrations of total phenols (80.13 mg of GAE/g) and total flavonoids (38.33 mg of quercetin/g). 100 % methanol extracts exhibited higher antioxidant activity in the DPPH assay (78.32 %, IC50 = 1.59 mg/ml) and ABTS assay (69.82 %, IC50 = 2.39 mg/ml). The bio-functional activity of crude extracts depended on their extract and concentration. The present study demonstrates that the macroalgae S. polycystum contains noteworthy secondary metabolites and natural antioxidants, indicating their potential utilization in various pharmacological and functional food applications. |
| first_indexed | 2024-03-08T22:54:58Z |
| format | Article |
| id | doaj.art-e5f66e96834642ba9e57158161038c0c |
| institution | Directory Open Access Journal |
| issn | 2772-753X |
| language | English |
| last_indexed | 2025-03-21T15:39:59Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry Advances |
| spelling | doaj.art-e5f66e96834642ba9e57158161038c0c2024-06-19T04:47:05ZengElsevierFood Chemistry Advances2772-753X2024-06-014100565Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determinationMohammad Khairul Alam Sobuj0Morshed Shamim Shemul1Md. Shoebul Islam2Md. Ariful Islam3Shayla Sultana Mely4Mehedi Hasan Ayon5Shahittya Mitra Pranto6Mohammad Shafiqul Alam7Mohammad Sarfuddin Bhuiyan8S.M. Rafiquzzaman9Marine Fisheries and Technology Station, Bangladesh Fisheries Research Institute, Cox's Bazar 4700, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, BangladeshShrimp Research Station, Bangladesh Fisheries Research Institute, Bagerhat 9300, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, BangladeshBangladesh Fisheries Research Institute, Mymensingh 2201, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, BangladeshDepartment of Genetics and Fish Breeding, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, BangladeshOn Farm Research Division, Bangladesh Agricultural Research Institute, Cox's Bazar 4700, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh; Corresponding author.Seaweeds possess considerable potential for developing and enhancing pharmaceutical drugs because of their wide variety as abundant sources of numerous bioactive secondary metabolites, making them well-suited for developing and enhancing pharmaceutical drugs. This study evaluated the antioxidant, secondary metabolites, total phenolic content, and total flavonoid content of various crude extracts (methanol, ethanol) and their fractions (50 % and 70 %) of Sargassum polycystum. Fourier transform infrared (FT‐IR) analysis was also performed to identify the active chemical composition of the crude extracts. The results showed that various extracts contained varying concentrations of terpenoid, saponin, phlobatannin, cardiac glycosides, phenolic, and flavonoid. FT-IR analysis confirmed the presence of phenols, carboxylic acid, ketones, ethers, aromatics, amides, and sulfonates. 100 % methanolic extract contained the maximum concentrations of total phenols (80.13 mg of GAE/g) and total flavonoids (38.33 mg of quercetin/g). 100 % methanol extracts exhibited higher antioxidant activity in the DPPH assay (78.32 %, IC50 = 1.59 mg/ml) and ABTS assay (69.82 %, IC50 = 2.39 mg/ml). The bio-functional activity of crude extracts depended on their extract and concentration. The present study demonstrates that the macroalgae S. polycystum contains noteworthy secondary metabolites and natural antioxidants, indicating their potential utilization in various pharmacological and functional food applications.http://www.sciencedirect.com/science/article/pii/S2772753X23003866Brown seaweedSargassum polycystumSecondary metabolitesFT‐IRTotal phenolic contentTotal flavonoid content |
| spellingShingle | Mohammad Khairul Alam Sobuj Morshed Shamim Shemul Md. Shoebul Islam Md. Ariful Islam Shayla Sultana Mely Mehedi Hasan Ayon Shahittya Mitra Pranto Mohammad Shafiqul Alam Mohammad Sarfuddin Bhuiyan S.M. Rafiquzzaman Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determination Food Chemistry Advances Brown seaweed Sargassum polycystum Secondary metabolites FT‐IR Total phenolic content Total flavonoid content |
| title | Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determination |
| title_full | Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determination |
| title_fullStr | Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determination |
| title_full_unstemmed | Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determination |
| title_short | Qualitative and quantitative phytochemical analysis of brown seaweed Sargassum polycystum collected from Bangladesh with its antioxidant activity determination |
| title_sort | qualitative and quantitative phytochemical analysis of brown seaweed sargassum polycystum collected from bangladesh with its antioxidant activity determination |
| topic | Brown seaweed Sargassum polycystum Secondary metabolites FT‐IR Total phenolic content Total flavonoid content |
| url | http://www.sciencedirect.com/science/article/pii/S2772753X23003866 |
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