Blood-brain barrier permeability analysis of plant ceramides.

Ceramides, a type of sphingolipid, are cell membrane components and lipid mediators that modulate a variety of cell functions. In plants, ceramides are mostly present in a glucosylated glucosylceramide (GlcCer) form. We previously showed that oral administration of konjac-derived GlcCer to a mouse m...

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Bibliographic Details
Main Authors: Koichi Eguchi, Daisuke Mikami, Hui Sun, Takuya Tsumita, Kaori Takahashi, Katsuyuki Mukai, Kohei Yuyama, Yasuyuki Igarashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241640