Independent validation of stromal uPA in ABCSG-08: Level 1b evidence for the prognostic value of uPA immunohistochemistry

Independent validation of stromal uPA in ABCSG-08: Level 1b evidence for the prognostic value of uPA immunohistochemistry

Purpose: To validate the prognostic role of urokinase-type plasminogen-activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1) protein expression in FFPE archived tumor samples when assessed by immunohistochemistry. Patients and methods: Fresh-frozen, paraffin-embedded (FFPE) samples from...

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Bibliographic Details
Main Authors: C.F. Singer, S.W. Jahn, M. Rudas, Z. Bago-Horvath, F. Fitzal, L. Abete, F. Moinfar, M. Gnant, M. Filipits
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Breast
Subjects:
Urokinase plasminogen activator (uPA)
Plasminogen activator Inhibitor-1 (PAI-1)
ABCSG 8
Adjuvant endocrine therapy
Breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977622000959

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http://www.sciencedirect.com/science/article/pii/S0960977622000959

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