The Expression of ephrinA1/ephA2 Receptor Increases in Chronic Rhinosinusitis and ephrinA1/ephA2 Signaling Affects Rhinovirus-Induced Innate Immunity in Human Sinonasal Epithelial Cells

The Expression of ephrinA1/ephA2 Receptor Increases in Chronic Rhinosinusitis and ephrinA1/ephA2 Signaling Affects Rhinovirus-Induced Innate Immunity in Human Sinonasal Epithelial Cells

EphA2 receptor and its ephrin ligands are involved in virus infection, epithelial permeability, and chemokine secretion. We hypothesized that ephrinA1/ephA2 signaling participates in rhinovirus (RV)-induced antiviral immune response in sinonasal mucosa of patients with chronic rhinosinusitis (CRS)....

Full description

Bibliographic Details
Main Authors: Sang Hag Lee, Sung Hoon Kang, Mun Soo Han, Ji Won Kwak, Hyeon Geun Kim, Tae Hoon Lee, Da Bin Lee, Tae Hoon Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
ephrinA1/ephA2 signaling
chronic rhinosinusitis with nasal polyps
chronic rhinosinusitis without nasal polyps
type I interferon
type III interferon
interferon stimulated genes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.793517/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.793517/full

Similar Items