Surface functionalization-specific binding of coagulation factors by zinc oxide nanoparticles delays coagulation time and reduces thrombin generation potential in vitro.

Surface functionalization-specific binding of coagulation factors by zinc oxide nanoparticles delays coagulation time and reduces thrombin generation potential in vitro.

Zinc oxide nanoparticles (ZnO NPs) have many biomedical applications such as chemotherapy agents, vaccine adjuvants, and biosensors but its hemocompatibility is still poorly understood, especially in the event of direct contact of NPs with blood components. Here, we investigated the impact of size a...

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Bibliographic Details
Main Authors: Jun-Young Yang, Jiyeong Bae, Ayoung Jung, Seonyeong Park, Seungtae Chung, Jihyun Seok, Hangsik Roh, Youngju Han, Jae-Min Oh, Soojung Sohn, Jayoung Jeong, Wan-Seob Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5517067?pdf=render

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http://europepmc.org/articles/PMC5517067?pdf=render

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