Fecal Microbial Signatures Are Associated With Engraftment Failure Following Umbilical Cord Blood Transplantation in Pediatric Crohn’s Disease Patients With IL10RA Deficiency

Fecal Microbial Signatures Are Associated With Engraftment Failure Following Umbilical Cord Blood Transplantation in Pediatric Crohn’s Disease Patients With IL10RA Deficiency

ObjectivesUmbilical cord blood transplantation (UCBT) is associated with a relatively high rate of engraftment failure. This study aimed at exploring whether any fecal microbiota could be associated with engraftment failure following UCBT in Crohn’s disease patients with IL10RA deficiency.MethodsThi...

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Bibliographic Details
Main Authors: Aijuan Xue, Xiaowen Qian, Xuefeng Gao, Ping Wang, Lin Wang, Cuifang Zheng, Zhiheng Huang, Wenhui Hu, Jieru Shi, Ying Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
Crohn’s disease
IL10RA
pediatric
microbiome
umbilical cord blood transplantation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.580817/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.580817/full

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