Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy

Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy

Background Dilated cardiomyopathy (DCM) is a major cause of heart failure in children. Despite intensive genetic analyses, pathogenic gene variants have not been identified in most patients with DCM, which suggests that cardiomyocytes are not solely responsible for DCM. Cardiac fibroblasts (CFs) are...

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Bibliographic Details
Main Authors: Hirofumi Tsuru, Chika Yoshihara, Hidehiro Suginobe, Mizuki Matsumoto, Yoichiro Ishii, Jun Narita, Ryo Ishii, Renjie Wang, Atsuko Ueyama, Kazutoshi Ueda, Masaki Hirose, Kazuhisa Hashimoto, Hiroki Nagano, Ryosuke Tanaka, Takaharu Okajima, Keiichi Ozono, Hidekazu Ishida
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac fibroblast
cardiomyocyte
dilated cardiomyopathy
pediatric
RNA‐seq
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.029676

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https://www.ahajournals.org/doi/10.1161/JAHA.123.029676

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