Carnosic Acid Attenuates an Early Increase in ROS Levels during Adipocyte Differentiation by Suppressing Translation of Nox4 and Inducing Translation of Antioxidant Enzymes

Carnosic Acid Attenuates an Early Increase in ROS Levels during Adipocyte Differentiation by Suppressing Translation of Nox4 and Inducing Translation of Antioxidant Enzymes

The objective of this study was to investigate molecular mechanisms underlying the ability of carnosic acid to attenuate an early increase in reactive oxygen species (ROS) levels during MDI-induced adipocyte differentiation. The levels of superoxide anion and ROS were determined using dihydroethidiu...

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Bibliographic Details
Main Authors: Dae-Kun Lee, Hae-Dong Jang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
carnosic acid
ROS generation
ROS neutralization
Nox4 enzyme translation
NF-κB translocation
IkBα phosphorylation
Online Access:https://www.mdpi.com/1422-0067/22/11/6096

Internet

https://www.mdpi.com/1422-0067/22/11/6096

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