Cognitive dysfunction, elevated anxiety and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice

The circadian clock comprises a set of genes involved in cell-autonomous transcriptional feedback loops that orchestrate the expression of a range of downstream genes, driving circadian patterns of behavior. Cognitive dysfunction, mood disorders, anxiety disorders and substance abuse disorders have...

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Bibliographic Details
Main Authors: Dimitri eDe Bundel, Giuseppe eGangarossa, Anne eBiever, Xavier eBonnefont, Emmanuel eValjent
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00152/full