Role of the SDF-1/CXCR4 signaling pathway in cartilage and subchondral bone in temporomandibular joint osteoarthritis induced by overloaded functional orthopedics in rats

Role of the SDF-1/CXCR4 signaling pathway in cartilage and subchondral bone in temporomandibular joint osteoarthritis induced by overloaded functional orthopedics in rats

Abstract Objectives To (i) use a mandibular advancement appliance in rats to investigate the role of the stromal cell-derived factor/CXC receptor 4 (SDF-1/CXCR4) signaling pathway in temporomandibular joint osteoarthritis (TMJ OA) induced by overloaded functional orthopedics (OFO) and (ii) provide a...

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Bibliographic Details
Main Authors: Jing Yang, Yazhen Li, Ying Liu, Qiang Zhang, Qi Zhang, Junbo Chen, Xiao Yan, Xiao Yuan
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Temporomandibular joint osteoarthritis; Overloaded functional orthopedics; Subchondral bone; SDF-1/CXCR4
Online Access:http://link.springer.com/article/10.1186/s13018-020-01860-x

Internet

http://link.springer.com/article/10.1186/s13018-020-01860-x

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