Preliminary study of improving immune tolerance in vivo of bioprosthetic heart valves through a novel antigenic removal method

Preliminary study of improving immune tolerance in vivo of bioprosthetic heart valves through a novel antigenic removal method

The durability of bioprosthetic heart valves is always compromised by the inherent antigenicity of biomaterials. Decellularization has been a promising approach to reducing the immunogenicity of biological valves. However, current methods are insufficient in eliminating all immunogenicity from the b...

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Bibliographic Details
Main Authors: Mingzhe Song, Liang Yi, Zhenjie Tang, Xinlong Xie, Yuhong Liu, XiaoKe Qi, Zhenlin Jiang, ZeGuo Chen, Chunyang Chen, QiYing Wu, ZhongShi Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
biomaterial
ionic detergent
immunogenicity
bioprosthetic heart valves;
decellualrization
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1141247/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1141247/full

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