Spatial architectures of somatic mutations in normal prostate, benign prostatic hyperplasia and coexisting prostate cancer

Spatial architectures of somatic mutations in normal prostate, benign prostatic hyperplasia and coexisting prostate cancer

Abstract This study aimed to identify somatic mutations in nontumor cells (NSMs) in normal prostate and benign prostatic hyperplasia (BPH) and to determine their relatedness to prostate cancer (PCA). From 22 PCA patients, two prostates were sampled for 3-dimensional mapping (50 normal, 46 BPH and 1...

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Bibliographic Details
Main Authors: Jeesoo Chae, Seung-Hyun Jung, Eun Ji Choi, Jae Woong Kim, Na Yung Kim, Sung Won Moon, Ji Youl Lee, Yeun-Jun Chung, Sug Hyung Lee
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01140-8

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https://doi.org/10.1038/s12276-023-01140-8

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