Mir-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1

Mir-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1

Osteosarcoma is the most common type of bone cancer in children and adolescents. Impaired differentiation of osteoblast cells is a distinguishing feature of this aggressive disease. As improvements in survival outcomes have largely plateaued, better understanding of the bone differentiation program...

Full description

Bibliographic Details
Main Authors: Yevgeniy eGindin, Yuan eJiang, Princy eFrancis, Robert L Walker, Ogan D Abaan, Yuelin J Zhu, Paul S Meltzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Genetics
Subjects:
Bone and Bones
Osteosarcoma
differentiation
MicroRNA (miRNA)
GJA1
MiR-23a
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00233/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00233/full

Similar Items