Pimavanserin treatment increases plasma brain-derived neurotrophic factor levels in rats

BackgroundPimavanserin, a serotonin 5HT-2A receptor inverse agonist is the first-line, FDA-approved treatment of hallucinations and delusions associated with Parkinson’s Disease psychosis (PDP), which occurs in up to 50% of PD patients. The neurobiological mechanism underlying the therapeutic effect...

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Bibliographic Details
Main Authors: Ashutosh Tripathi, Henry A. Nasrallah, Anilkumar Pillai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1237726/full