A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest

A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest

Abstract Enhancer-promoter interactions preferentially occur within boundary-insulated topologically associating domains (TADs), limiting inter-TAD interactions. Enhancer clusters in linear proximity, termed super-enhancers (SEs), ensure high target gene expression levels. Little is known about SE t...

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Bibliographic Details
Main Authors: Sandra Kessler, Maryline Minoux, Onkar Joshi, Yousra Ben Zouari, Sebastien Ducret, Fiona Ross, Nathalie Vilain, Adwait Salvi, Joachim Wolff, Hubertus Kohler, Michael B. Stadler, Filippo M. Rijli
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38953-0

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https://doi.org/10.1038/s41467-023-38953-0

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