CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells

Cancer: Clocking the triggers for tumor progression Two proteins involved in regulating circadian rhythms may promote cancer tumor growth by changing the internal structures of cells. Circadian clock proteins play key roles in cell division, metabolism, and immune responses. Certain clock proteins a...

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Bibliographic Details
Main Authors: Teng-jiao Ma, Zhi-wei Zhang, Yi-lu Lu, Ying-ying Zhang, Da-chang Tao, Yun-qiang Liu, Yong-xin Ma
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0156-4