Cooperative nuclear localization sequences lend a novel role to the N-terminal region of MSH6.

Cooperative nuclear localization sequences lend a novel role to the N-terminal region of MSH6.

Human mismatch repair proteins MSH2-MSH6 play an essential role in maintaining genetic stability and preventing disease. While protein functions have been extensively studied, the substantial amino-terminal region (NTR*) of MSH6 that is unique to eukaryotic proteins, has mostly evaded functional cha...

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Bibliographic Details
Main Authors: Natalie R Gassman, Jill E Clodfelter, Anita K McCauley, Keith Bonin, Freddie R Salsbury, Karin D Scarpinato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060103?pdf=render

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http://europepmc.org/articles/PMC3060103?pdf=render

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