The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1

The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1

The biogenesis of 60S ribosomal subunits is initiated in the nucleus where rRNAs and proteins form pre-60S particles. These pre-60S particles mature by transiently interacting with various assembly factors. The ~5000 amino-acid AAA+ ATPase Rea1 (or Midasin) generates force to mechanically remove ass...

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Bibliographic Details
Main Authors: Piotr Sosnowski, Linas Urnavicius, Andreas Boland, Robert Fagiewicz, Johan Busselez, Gabor Papai, Helgo Schmidt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
Rea1
midasin
CryoEM
ribosome maturation
AAA+ protein
molecular machine
Online Access:https://elifesciences.org/articles/39163

Internet

https://elifesciences.org/articles/39163

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