Cloning and Expression of Truncated Protein of Epidermal Growth Factor-1 (EGFR-1) in Pichia Pastoris Yeast Host

Cloning and Expression of Truncated Protein of Epidermal Growth Factor-1 (EGFR-1) in Pichia Pastoris Yeast Host

Background: Epidermal growth factor receptor (EGFR) plays a major role in the pathophysiology of a wide variety of solid tumors such as glioblastoma and breast cancer. Therefore, blocking of signaling cascade of this receptor via specific antibodies is an appropriate therapeutic target against these...

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Bibliographic Details
Main Authors: Javad Zavar-Reza, Nader Khaleghi, Ali Hatami, Masumeh Heidari, Reza Mansuri-Majumerd, Mohammad Hasan Sheikhha, Majid Mojarrad
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2016-02-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Epidermal growth factor receptor (EGFR)
Human glioma cell line (A172)
Recombinant protein
Plasmid pPicZalphaA
Yeast
Pichia pastoris
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/5306

Internet

http://jims.mui.ac.ir/index.php/jims/article/view/5306

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