New treatment alternatives for primary and metastatic colorectal cancer by an integrated transcriptome and network analyses

Abstract Metastatic colorectal cancer (CRC) is still in need of effective treatments. This study applies a holistic approach to propose new targets for treatment of primary and liver metastatic CRC and investigates their therapeutic potential in-vitro. An integrative analysis of primary and metastat...

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Bibliographic Details
Main Authors: Caner Karaca, Ezgi Demir Karaman, Asim Leblebici, Hasan Kurter, Hulya Ellidokuz, Altug Koc, Ender Berat Ellidokuz, Zerrin Isik, Yasemin Basbinar
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-59101-8