Efficacy and safety of secukinumab for the treatment of severe ABCA12 deficiency‐related ichthyosis in a child

Summary Background Patients with severe autosomal recessive congenital ichthyosis (ARCI) show a T helper 17/interleukin 17 (Th17/IL17) skewing in their skin and serum, resembling the inflammatory profile of psoriatic patients. Secukinumab, an IL‐17A inhibitor, has shown clinical efficacy in patients...

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Bibliographic Details
Main Authors: J. Yogarajah, C. Gouveia, J. Iype, S. Häfliger, A. Schaller, J.M. Nuoffer, M. Fux, M. Gautschi
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Skin Health and Disease
Online Access:https://doi.org/10.1002/ski2.25