Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2

Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2

Abstract Bacterial sepsis results in high mortality rates, and new therapeutics to control infection are urgently needed. Here, we investigate the therapeutic potential of fibrates in the treatment of bacterial sepsis and examine their effects on innate immunity. Fibrates significantly improved the...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Ivan Tancevski, Manfred Nairz, Kristina Duwensee, Kristina Auer, Andrea Schroll, Christiane Heim, Clemens Feistritzer, Julia Hoefer, Romana R Gerner, Alexander R Moschen, Ingrid Heller, Petra Pallweber, Xiaorong Li, Markus Theurl, Egon Demetz, Anna M Wolf, Dominik Wolf, Philipp Eller, Andreas Ritsch, Guenter Weiss
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	Springer Nature 2014-04-01
Cyfres:	EMBO Molecular Medicine
Pynciau:	chemokine receptor fenofibrate infection inflammation neutrophils
Mynediad Ar-lein:	https://doi.org/10.1002/emmm.201303415

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