Effect of chitooligosaccharide on the inhibition of SARS-CoV-2 main protease

Abstract Background The main protease (Mpro) is a crucial target for severe acute respiratory syndrome coronavirus (SARS-CoV-2). Chitooligosaccharide (CS) has broad-spectrum antiviral activity and can effectively inhibit the activity of SARS-CoV. Here, based on the high homology between SARS-CoV-2 a...

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Bibliographic Details
Main Authors: Qian Wang, Yuanyuan Song, Mungu Kim, Sei Kwang Hahn, Ge Jiang
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-02-01
Series:Biomaterials Research
Subjects:
Online Access:https://doi.org/10.1186/s40824-023-00351-4