The 26 S proteasome in Entamoeba histolytica: divergence of the substrate binding pockets from host proteasomes

The 26 S proteasome in Entamoeba histolytica: divergence of the substrate binding pockets from host proteasomes

Abstract Objective Proteasomes are conserved proteases crucial for proteostasis in eukaryotes and are promising drug targets for protozoan parasites. Yet, the proteasomes of Entamoeba histolytica remain understudied. The study’s objective was to analyse the differences in the substrate binding pocke...

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Bibliographic Details
Main Authors: Nidhi Joshi, SK Yasir Hosen, Mohd. Fahad, Anil Raj Narooka, S. Gourinath, Swati Tiwari
Format: Article
Language:English
Published: BMC 2024-08-01
Series:BMC Research Notes
Subjects:
Amoebiasis
Entamoeba histolytica
MG132
26S proteasomes
Protozoan parasite
Ubiquitin
Online Access:https://doi.org/10.1186/s13104-024-06848-y

Internet

https://doi.org/10.1186/s13104-024-06848-y

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