Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation, blood- brain barrier damage and brain oedema independently of infarct size

<p>Abstract</p> <p>Background</p> <p>Systemic inflammation impairs outcome in stroke patients and experimental animals via mechanisms which are poorly understood. Circulating inflammatory mediators can activate cerebrovascular endothelium or glial cells in the brain and...

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Bibliographic Details
Main Authors: Dénes Ádám, Ferenczi Szilamér, Kovács Krisztina J
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/8/1/164