Regulatory effects of statins on CCL2/CCR2 axis in cardiovascular diseases: new insight into pleiotropic effects of statins

Regulatory effects of statins on CCL2/CCR2 axis in cardiovascular diseases: new insight into pleiotropic effects of statins

Abstract Background HMG-CoA reductase inhibitors are well-known medications in the treatment of cardiovascular disorders due to their pleiotropic and lipid-lowering properties. Herein, we reviewed the effects of statins on the CCL2/CCR2 axis. Method Scopus and Pubmed databases were systematically se...

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Bibliographic Details
Main Authors: Hanieh Gholamalizadeh, Behzad Ensan, Sercan Karav, Tannaz Jamialahmadi, Amirhossein Sahebkar
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Inflammation
Subjects:
MCP-1
CCL2
Statins
Ischemic heart disease
Stroke
Online Access:https://doi.org/10.1186/s12950-024-00420-y

Internet

https://doi.org/10.1186/s12950-024-00420-y

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