Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes

Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes

Abstract Background The fruit of Phyllanthus emblica L., a traditional medicine in China and India, is used to treat diabetes mellitus. Its water extract (WEPE) has demonstrated hypoglycemic effects in diabetic rats, but its mechanisms on glucose utilization and insulin resistance in skeletal muscle...

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Bibliographic Details
Main Authors: Hai-yan Li, Chun-fei Li, Chun-hui Liu, Sun-ce Chen, Yi-fan Liu, Quan-he Lv, Wen Zhang
Format: Article
Language:English
Published: BMC 2024-08-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Phyllanthus emblica L.
Glucose uptake
AMP-activated protein kinase
Insulin sensitivity
C2C12 myotubes
Palmitate
Online Access:https://doi.org/10.1186/s12906-024-04592-1

Internet

https://doi.org/10.1186/s12906-024-04592-1

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