Advanced maternal age induces fetal growth restriction through decreased placental inflammatory cytokine expression and immune cell accumulation in mice

Advanced maternal age induces fetal growth restriction through decreased placental inflammatory cytokine expression and immune cell accumulation in mice

Advanced maternal age is a risk factor for female infertility, and placental dysfunction is considered one of the causes of pregnancy complications. We investigated the effects of advanced maternal aging on pregnancy outcomes and placental senescence. Female pregnant mice were separated into three g...

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Bibliographic Details
Main Authors: Yoshiki HIRATA, Yusuke KATSUKURA, Yuka HENMI, Ren OZAWA, Sayaka SHIMAZAKI, Akira KUROSAWA, Yasushi TORII, Hironori TAKAHASHI, Hisataka IWATA, Takehito KUWAYAMA, Koumei SHIRASUNA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2021-06-01
Series:The Journal of Reproduction and Development
Subjects:
aging
cellular senescence
inflammaging
immune cells
senescence-associated secretory phenotype (sasp)
Online Access:https://www.jstage.jst.go.jp/article/jrd/67/4/67_2021-034/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/jrd/67/4/67_2021-034/_pdf/-char/en

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