Structural organization of mammalian prions as probed by limited proteolysis.

Structural organization of mammalian prions as probed by limited proteolysis.

Elucidation of the structure of PrP(Sc) continues to be one major challenge in prion research. The mechanism of propagation of these infectious agents will not be understood until their structure is solved. Given that high resolution techniques such as NMR or X-ray crystallography cannot be used, a...

Full description

Bibliographic Details
Main Authors: Ester Vázquez-Fernández, Jana Alonso, Miguel A Pastrana, Adriana Ramos, Lothar Stitz, Enric Vidal, Irina Dynin, Benjamin Petsch, Christopher J Silva, Jesús R Requena
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3502352?pdf=render

Internet

http://europepmc.org/articles/PMC3502352?pdf=render

Similar Items